THE EXTRACYTOPLASMIC DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS SER/THR KINASE PKNB BINDS SPECIFIC MUROPEPTIDES AND IS REQUIRED FOR PKNB LOCALIZATION.

The extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localization.

The Mycobacterium tuberculosis Ser/Thr kinase PknB has been implicated in the regulation of cell growth and morphology in this organism.The extracytoplasmic domain of this membrane protein comprises four penicillin binding protein and Ser/Thr kinase associated (PASTA) domains, which are predicted to bind stem peptides of peptidoglycan.Using a compr

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MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling

Summary: Rett syndrome (RTT) is a severe neurological disorder, with impaired brain development caused by mutations in Fuel Rails MECP2; however, the underlying mechanism remains elusive.We know from previous work that MeCP2 facilitates the processing of a specific microRNA, miR-199a, by associating with the Drosha complex to regulate neuronal func

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trans-Dichloridobis(2,4-dimethylaniline-κN)palladium(II)

In the title compound, [PdCl2(C8H11N)2], the PdII atom is located on a crystallographic inversion center and adopts a square-planar coordination geometry, Dishwasher Filter Plate with pairs of equivalent ligands in trans positions.In the crystal, adjacent molecules are linked with each other through weak N—H.Cl hydrogen bonds and &#96

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